Abstract To investigate the functionality of A2B adenosine receptor (A2BAR) and the nitric oxide (NO) and vascular endothelial growth factor (VEGF) signaling pathway in the endothelial cell proliferation/migration during preeclampsia, we used human umbilical vein endothelial cells (HUVECs) isola...
Acurio J1, Celis C2, Perez J2, Escudero C3. Abstract OBJECTIVE: Either obesity or vocal loading task leads to elevation of proinflammatory cytokines such as interleukin 6 (IL-6). However, it is unknown whether vocal parameters after vocal loading are correlated with body mass index (BMI) o...
Felipe A. Zuniga, 1 Valeska Ormazabal, 2 Nicolas Gutierrez, 1 Valeria Aguilera, 1 Claudia Radojkovic, 1 Carlos Veas, 1Carlos Escudero, 3 Liliana Lamperti, 1 and Claudio Aguayo 1 Abstract The bioavailability of nitric oxide (NO) represents a key marker in vascular health. A decre...
Valeria Aguilera,1 Luis Briceño,1 Hector Contreras,2 Liliana Lamperti,1 Esperanza Sepúlveda,1 Francisca Díaz-Perez,1Marcelo León,1 Carlos Veas,1 Rafael Maura,3 Jorge Roberto Toledo,3 Paulina Fernández,1,4 Ambart Covarrubias,4Felipe Andrés Zuñiga,1 Claudia Radojkovic,1 Carlos Escud...
Carlos A. Escudero Development of placental vascular tree is structurally and functionally required for both adequate placental growth and delivery of nutrients from mother to the fetus. Impaired placental angiogenesis has been implicated in the pathophysiology of pregnancy complications which have...
González M1, Rojas S2, Avila P2, Cabrera L3, Villalobos R4, Palma C2, Aguayo C5, Peña E6, Gallardo V6, Guzmán-Gutiérrez E7, Sáez T4, Salsoso R4,Sanhueza C4, Pardo F4, Leiva A4, Sobrevia L8. Abstract Vascular tone is controlled by the L-arginine/nitric oxide (NO) pathway, and...
About this Research Topic Fetal growth is dependent on nutrient and oxygen availability, which in turn is related to maternal endowment and substrate transfer by the placenta into the fetal circulation. Indeed, any given substrate must traverse the placental blood barrier. Transfer across this...
About this Research Topic Recent findings show the potential role of insulin signaling in cardiovascular health, related with insulin receptors expression in cardiomyocytes and vascular cells. The epidemiological data show a correlation between insulin resistance/diabetes and cardiovascular dis...
El Dr. Carlos Escudero Orozco, quien lidera el Laboratorio de Fisiología Vascular e integra el Grupo de Investigación en Angiogénesis Tumoral (LFV-GIANT), fue nominado en atención a su destacado trabajo investigativo. Los académicos Dr. Patricio Oliva Moresco del Departamento de Nutrición y Sa...
Cerca de $5.000 millones, que se distribuirán entre 35 proyectos correspondientes a 11 planteles universitarios, fueron adjudicados en el III Concurso de Equipamiento Científico y Tecnológico, una iniciativa impulsada por la Comisión Nacional de Investigación Científica y Tecnológica, CONIC...